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Diastereoselective synthesis of α-amino-β-hydroxyacids |
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| Authors: | Giuseppe Guanti Luca Banfi Enrica Narisano Carlo Scolastico |
| Affiliation: | 1. Istituto di Chimica Organica dell''Università, Centro C.N.R. di Studio sui Diariloidi e loro Applicazioni, Palazzo delle Scienze, Corso Europa, 16132 Genova, Italy;2. Istituto di Chimica Organica dell''Università, Via Venezian 21, 20133 Milano, Italy |
| Abstract: | threo-α-Dibenzylamino-?-hydroxyesters (2) have been synthesised with high diastereoselectivity through the NaBH4 reduction of α-dibenzylamino-β-oxoesters (4) and then tranformed into threo-α-amino-β-hydroxyacids. |
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