|
|||||
|
|
In Vitro Studies on the Relationship Between the Antioxidant Activities of Some Berry Extracts and Their Binding Properties to Serum Albumin |
|
| Authors: | Jacek Namiesnik Kann Vearasilp Alina Nemirovski Hanna Leontowicz Maria Leontowicz Pawel Pasko Alma Leticia Martinez-Ayala Gustavo A. González-Aguilar Milan Suhaj Shela Gorinstein |
| Affiliation: | 1. Department of Analytical Chemistry, Chemical Faculty, Gdańsk University of Technology, 80952, Gdańsk, Poland 2. Faculty of Pharmacy, Srinakharinwirot University, Bangkok, Thailand 3. The Institute for Drug Research, School of Pharmacy, Hadassah Medical School, The Hebrew University, Jerusalem, 91120, Israel 4. Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences (SGGW), Warsaw, Poland 5. Department of Food Chemistry and Nutrition, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688, Krakow, Poland 6. Centro de Desarrollo de Productos Bioticos, Instituto Politécnico Nacional, Carretera Yautepec-Jojutla, Km. 6, calle CEPROBI No. 8, Col. San Isidro, Yautepec, Morelos, 62731, México 7. Research Center for Food & Development, A.C. (CIAD), Carretera a Ejido La Victoria, Km 0.6, Hermosillo, Sonora, 83304, Mexico 8. Food Research Institute, 82475, Bratislava, Slovakia |
| Abstract: | The aim of this study was to investigate the possibility to use the bioactive components from cape gooseberry (Physalis peruviana), blueberry (Vaccinium corymbosum), and cranberry (Vaccinium macrocarpon) extracts as a novel source against oxidation in food supplementation. The quantitative analysis of bioactive compounds (polyphenols, flavonoids, flavanols, carotenoids, and chlorophyll) was based on radical scavenging spectrophometric assays and mass spectrometry. The total phenolic content was the highest (P?1-picrylhydrazyl radical scavenging assay and Cupric reducing antioxidant capacity were in water extracts of blueberries, showing 108.1?±?7.2 and 131.1?±?9.6 μMTE/g DW with correlation coefficients of 0.9918 and 0.9925, and by β-carotene linoleate assay at 80.1?±?6.6 % with correlation coefficient of 0.9909, respectively. The water extracts of berries exhibited high binding properties with human serum albumin in comparison with quercetin. In conclusion, the bioactive compounds from a relatively new source of gooseberries in comparison with blueberries and cranberries have the potential as food supplementation for human health. The antioxidant and binding activities of berries depend on their bioactive compounds. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |