Bismuth-catalyzed benzylic oxidations with tert-butyl hydroperoxide |
| |
| Authors: | Bonvin Yannick Callens Emmanuel Larrosa Igor Henderson David A Oldham James Burton Andrew J Barrett Anthony G M |
| |
| Institution: | Department of Chemistry, Imperial College London, Exhibition Road, London SW7 2AZ, England. |
| |
| Abstract: | reaction: see text] Oxidation of alkyl and cycloalkyl arenes with tert-butyl hydroperoxide catalyzed by bismuth and picolinic acid in pyridine and acetic acid gave the corresponding benzylic ketones (48-99%). Alternatively, oxidation of methyl arenes gave the corresponding substituted benzoic acids (50-95%). Preliminary mechanistic studies were consistent with a radical mechanism rather than a bismuth(III)-bismuth(V) cycle. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
