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Approach to a better understanding and modelling of β-pyrrolidinoalcohol ligands for enantioselective alkylation |
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| Authors: | Antnio M d&#x;A Rocha Gonsalves M Elisa S Serra Dina Murtinho |
| Institution: | Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal |
| Abstract: | A series of pyrrolidine-based β-amino alcohols derived from malic acid, citramalic acid and pantolactone with primary amines was prepared and their activity as chiral ligands in the enantioselective alkylation of benzaldehyde using diethylzinc was studied. |
| Keywords: | Enantioselective alkylation β-Amino alcohols Diethylzinc Pyrrolidinoalcohols Benzaldehyde |
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