A facile aminocyclization for the synthesis of pyrrolidine and piperidine derivatives |
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| Authors: | Shao Zhihui Chen Jingbo Tu Yongqiang Li Liang Zhang Hongbin |
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| Affiliation: | School of Pharmacy, Yunnan University, Kunming, Yunnan 650091, PR China. |
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| Abstract: | ![]()
Bromination of an isolated double bond followed by aminocyclization furnishes a highly stereoselective protocol for the intramolecular formation of pyrrolidine and piperidine ring containing subunits that are presented in numerous biologically active natural products. |
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