| 分子印迹电位型传感器快速检测猪尿液中的克伦特罗 |
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| 引用本文： | 梁荣宁,高奇,秦伟. 分子印迹电位型传感器快速检测猪尿液中的克伦特罗[J]. 分析化学, 2012, 40(3): 354-358. DOI: 10.3724/SP.J.1096.2012.10890 |
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| 作者姓名： | 梁荣宁 高奇 秦伟 |
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| 作者单位： | 1.中国科学院烟台海岸带研究所,中国科学院及山东省海岸带环境过程重点实验室,烟台264003;2.中国科学院烟台海岸带研究所,中国科学院及山东省海岸带环境过程重点实验室,烟台264003;中国科学院研究生院,北京100049 |
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| 基金项目： | 国家自然科学基金(No.20977073);山东省自然科学杰出青年基金(No.JQ200814);山东省“泰山学者”人才计划项目资助 |
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| 摘 要： | 以盐酸克伦特罗为模板分子,采用沉淀聚合法合成了克伦特罗的分子印迹聚合物,并以其为离子载体,制得分子印迹聚合物膜克伦特罗离子选择性电极.在最优实验条件下,电极对克伦特罗阳离子的检出限可达7.0×10-8mol/L,线性范围为1.0×10 7～1.0×10-4 mol/L,能斯特斜率为55.7 mV/decade.此电极具有优越的选择性、快速的响应时间以及良好的稳定性;已成功应用于实际猪尿样品中克伦特罗的测定,加标回收率为98％～107％,检测时间小于3 min.
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| 关 键 词： | 分子印迹聚合物 电位型传感器 克伦特罗 |
Potentiometric Sensor Based on Molecularly Imprinted Polymer for Rapid Determination of Clenbuterol in Pig Urine |
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| LIANG Rong-Ning,GAO Qi,QIN Wei. Potentiometric Sensor Based on Molecularly Imprinted Polymer for Rapid Determination of Clenbuterol in Pig Urine[J]. Chinese Journal of Analytical Chemistry, 2012, 40(3): 354-358. DOI: 10.3724/SP.J.1096.2012.10890 |
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| Authors: | LIANG Rong-Ning GAO Qi QIN Wei |
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| Affiliation: | 1 1(Chinese Academy of Sciences and Shandong Provincial Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research,Chinese Academy of Sciences,Yantai 264003,China) 2(Graduate University of Chinese Academy of Sciences,Beijing 100049,China) |
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| Abstract: | A polymeric membrane ion-selective electrode for the determination of clenbuterol is described.It is based on a molecularly imprinted polymer(MIP) as an ionophore for molecular recognition,which can be synthesized by precipitation polymerization using clenbuterol hydrochloride as a template molecule.Under the optimized conditions,the proposed membrane electrode exhibits Nernstian response to the protonated clenbuterol over the concentration range of 1.0×10-7-1.0×10-4 mol/L with a slope of 55.7 mV/decade,and the detection limit is 7.0×10-8 mol/L.The MIP-based sensor shows excellent selectivity,rapid response time and satisfactory long-term stability.The potentiometric sensor has been successfully applied to determine the clenbuterol in pig urine samples with recoveries between 98% and 107% and an analytical time of less than 3 min. |
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| Keywords: | Molecularly imprinted polymer Potentiometric sensor Clenbuterol |
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