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Botulinum Toxin Type B for Treatment of Spasmodic Dysphonia: A Case Report
Authors:Robert Thayer Sataloff MD  Yolanda D Heman-Ackah  Lance L Simpson  Jong-Beak Park  Amy Zwislewski  Caren Sokolow  Steven Mandel
Institution:Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Phillyent.com
Abstract:Although treatment with botulinum toxin type A (BTXA) has become the standard of care for most patients with laryngeal dystonia, its use is limited by the development of resistance to the toxin in some patients. Botulinum toxin type B (BTXB) has been found to be safe and effective in the treatment of cervical dystonia, but it has not been used previously to treat spasmodic dysphonia. Our experience with BTXB in a patient who developed resistance to BTXA suggests that BTXB may be safe and effective for the treatment of laryngeal dystonia, as well.
Keywords:Botulinum toxin  Spasmodic dysphonia  Laryngeal dystonia  Botulinum toxin B
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