Preparation and Antifungal Activity of 3-Iodo- and 6-Iodo-8-quinolinols |
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Authors: | Herman Gershon Donald D Clarke John J McMahon Muriel Gershon |
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Institution: | (1) Department of Chemistry, Fordham University, Bronx, NY 10458-9993, USA, US;(2) New York Botanical Garden, Bronx, NY 10458-9993, USA, US |
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Abstract: | Summary. 3-Iodo- and 6-Iodo-8-quinolinols were prepared and tested against six fungi: Aspergillus niger, A. oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton mentagrophytes in Sabouraud dextrose broth. A comparison with the previously known 5-iodo- and 7-iodo-8-quinolinols showed that the 6-iodo isomer was
the most active.
Corresponding author. E-mail: clarke@fordham.edu
Received May 15, 2002; accepted June 11, 2002 |
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Keywords: | , ,3-Iodo-8-quinolinol, 6-Iodo-8-quinolinol, Antifungal activity |
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