Experimental Modeling of Formation of the Basic Mineral Phases of Calcifications |
| |
Authors: | O A Golovanova |
| |
Institution: | 1.Dostoevsky Omsk State University,Omsk,Russia |
| |
Abstract: | Calcium phosphate phase formation was studied under process conditions involving human blood plasma. Calcium phosphate was synthesized with variable supersaturation (S) and experimental time. It was found that a non-stoichiometric hydrated carbonated hydroxyapatite, identical in the composition to calcifications in humans, is formed under the experimental conditions. The highest amount of carbonate ions (5.54 wt %) in the solid phase corresponds to the apatite synthesized at S = 50 for 10 weeks. The dissolution rate of solid phases was determined by mathematical processing of the obtained kinetic curves; this can be used to find compounds able to stop the development of vascular calcinosis. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|