| Investigation of Aconitine-type Alkaloids from Processed Tuber of Aconitum carmiechaeli by HPLC-ESI-MS/MS~n |
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| 作者姓名： | Introduction Aconitine-type alkaloids isolated from the roots of Aconitum carmiechaeli show a potential toxicity and a broad spectrum of bioactivity[-]. On the basis of the C-substituent of C-diterpenoid skeleton aconitinetype alkaloids can be divided into diester-diterpenoid alkaloids |
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| 作者单位： | [1]Changchun Center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China [2]Graduate School of the Chinese Academy of Sciences, Beijing 100039, P. R. China |
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| 基金项目： | Supported by the National Natural Science Foundation of China（Nos. 30472134 and 30672600） and the National Basic Research Program of China（ No. 2006CB5047060）. |
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| 摘 要： | Introduction Aconitine-type alkaloids isolated from the roots of Aconitum carmiechaeli show a potential toxicity and a broad spectrum of bioactivity1-4].On the basis of the C8-substituent of C19-diterpenoid skeleton,aconitine-type alkaloids can be divided into diester-diterpenoid alkaloids(DDAs),monoester-diterpenoid alkaloids(MDAs),and lipo-alkaloids(Fig.1).
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| 关 键 词： | 乌头碱 生物碱 乌头 提取 药用成分 |
| 收稿时间： | 29 November 2006 |
| 修稿时间： | 2006-11-29 |
Investigation of Aconitine-type Alkaloids from Processed Tuber of Aconitum carmiechaeli by HPLC-ESI-MS/MS |
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| Hao YUE, Zi-feng PI, Yu-feng ZHAO, Feng-rui SONG, Zhi-qiang LIU,Shu-ying LIU,.Investigation of Aconitine-type Alkaloids from Processed Tuber of Aconitum carmiechaeli by HPLC-ESI-MS/MS~n[J].Chemical Research in Chinese University,2007,23(5):625-627. |
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| Authors: | Hao YUE Zi-feng PI Yu-feng ZHAO Feng-rui SONG Zhi-qiang LIU Shu-ying LIU |
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| Institution: | aChangchun Center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China;bGraduate School of the Chinese Academy of Sciences, Beijing 100039, P. R. China |
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| Abstract: | Introduction Aconitine-type alkaloids isolated from the roots of Aconitum carmiechaeli show a potential toxicity and a broad spectrum of bioactivity1-4]. On the basis of the C8-substituent of C19-diterpenoid skeleton, aconitinetype alkaloids can be divided into diester-diterpenoid alkaloids( DDAs), monoester-diterpenoid alkaloids(MDAs), and lipo-alkaloids( Fig. 1 ). |
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| Keywords: | Aconitine-type alkaloids HPLC-ESI-MS/MSn Aconitum carmiechaeli |
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