KF/Al2O3 as an Efficient,Green, and Reusable Catalytic System for the Solvent-Free Synthesis of N-Alkyl Derivatives of Sulfonamides via Michael Reactions |
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| Authors: | Abdolkarim Zare Alireza Hasaninejad Mohammad Hassan Beyzavi Ahmad Reza Moosavi-Zare Ali Khalafi-Nezhad Mehrnoosh Roshankar |
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| Institution: | 1. Department of Chemistry , Payame Noor University (PNU) , Bushehr, Iran;2. Department of Chemistry, Faculty of Sciences , Persian Gulf University , Bushehr, Iran;3. Department of Chemistry, College of Sciences , Shiraz University , Shiraz, Iran |
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| Abstract: | KF/Al 2 O 3 efficiently catalyzes the microwave-assisted Michael addition of sulfonamides to α,β-unsaturated esters under solvent-free conditions to afford N-alkyl derivatives of sulfonamides as biologically interesting compounds in high yields and in short reaction times. In this reaction, N,N-dialkylsulfonamides are also produced, but in very low yields. |
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| Keywords: | N-alkylsulfonamide KF/Al2O3 Michael addition microwave solvent-free sulfonamide |
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