New Biologically Active N-(Tetrahydrobenzothienopyrimidin-4-YL)-Amino Acids,Thiourethane, Sulfonamides and Related Compounds

Abstract

Some derivatives of thieno[2,3-d]pyrimidine containing amino acids 3a-i, imidazoles 4a-f, isothiocyanate 5, thiourethane 6, triazine 8, pyrimidine 10, sulphonamides 13a-d, 14, pyrazole 16 and pyrazolone 17 were synthesized. The structural assignments of the new compounds were based on analytical, spectroscopic measurements and chemical reactions. Some of the obtained compounds showed interesting antimicrobial activities.