Dipolar Cycloaddition Reactions with Thiazolonylhydrazones: A New Route for the Synthesis of Several New Thienyl- and Furyl-Thiazolonylpyrrolopyrazole Derivatives of Expected Biological Activities |
| |
| Authors: | Hatem M Gaber |
| |
| Institution: | National Organization for Drug Control and Research , Cairo, Egypt |
| |
| Abstract: | Several new pyrrolopyrazoles were synthesized via the reactions of each of 2-thiophenecarboxaldehyde thiazolonylhydrazone or 2-furaldehyde thiazolonylhydrazone with N -substituted maleimides followed by partial dehydogenation using bromobenzene and complete aromatization using nitrobenzene. Structures were established on the basis of elemental analyses and spectroscopic data studies. |
| |
| Keywords: | Cycloaddition Reactions Furans N -substituted Maleimides Pyrrolopyrazoles Thiazolinones Thiophenes |
|
