A Facile One-Pot Synthesis of Highly-Functionalized Stable Heterocyclic Phosphorus Ylides in Aqueous Media |
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Authors: | Mohammad Reza Islami Zahra Hassani Hassan Sheibani |
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Institution: | Department of Chemistry, Faculty of Sciences , Shahid Bahonar University of Kerman , Kerman, Iran |
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Abstract: | Phthalimide or succinimide undergo a reaction with dialkyl acetylenedicarboxylates and triphenylphosphine to produce highly-functionalized stable heterocyclic phosphorus ylides in good yields in water-tetrahydrofuran (6:1). This methodology is of interest because of the use of water as solvent, thus minimizing the cost, operational hazards, and environmental pollution. |
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Keywords: | Heterocyclic Phosphorus Ylides Dialkyl Acetylenedicarboxylate |
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