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Regioselective Syntheses of 1-Aryl-substituted-5H-[1,3]thiazolo[3,2-a]quinazoline-5-ones During Sonogashira Coupling |
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| Authors: | Mohammad Bakherad Ali Keivanloo Zahra Kalantar Vahid Keley |
| Institution: | School of Chemistry , Shahrood University of Technology , Shahrood , Iran |
| Abstract: | Abstract Reaction of 2-mercaptopropargylquinazoline-4-one with various aryliodides catalyzed by Pd–Cu leads to the regioselective formation of 1-arylsubstituted-5H-1,3]thiazolo-3,2-a]quinazoline-5-ones. GRAPHICAL ABSTRACT  |
| Keywords: | Aryl iodide Pd-catalyzed quinazoline Sonogashira coupling thiazoloquinazoline |