New polyhydroxylated metabolite derived from biotransformation of diosgenin by the white-rot fungus Coriolus versicolor |
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| Authors: | Guang Wei Wu Xiao Jun Li Yi Gao Yuan Jia Jin Ming Gao |
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| Institution: | a College of Science, Northwest A & F University, Yangling, Shanxi 712100, China;b National Engineering Research Center for Phytochemistry in West China, Yangling, Shaanxi 712100, China |
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| Abstract: | Microbial transformation of diosgenin(1)was carried out with the white-rot fungus,Coriolus versicolor.A new polyhydroxyl metabolite,(25R)-spirost-5-ene-3β,7β,21-triol(2),was obtained as a result of hydroxylation.Its structure was elucidated on the basis of 1D and 2D NMR as well as HR-ESI-MS spectroscopic analysis. |
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| Keywords: | Coriolus versicolor Diosgenin Microbial biotransformation Biocatalysis |
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