Water-soluble peptide-coated nanoparticles: control of the helix structure and enhanced differential binding to immune cells |
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| Authors: | Rio-Echevarria Iria M Tavano Regina Causin Valerio Papini Emanuele Mancin Fabrizio Moretto Alessandro |
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| Institution: | Dipartimento di Scienze Chimiche, Università di Padova, via Marzolo 1, 35131 Padova, Italy. |
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| Abstract: | The stabilizing action of C(α)-tetrasubstituted α-amino acids inserted into a sequence of short peptides allowed for the first time the preparation of water-soluble nanoparticles of different materials coated with a helix-structured undecapeptide. This peptide coating strongly favors nanoparticle uptake by human immune system cells. |
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