Study of enzyme inhibitory activities by dipyridamole |
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| Authors: | T Noro M Ehara A Ueno |
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| Affiliation: | School of Pharmaceutical Sciences, University of Shizuoka, Japan. |
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| Abstract: | ![]()
Inhibitory activities of Dipyridamole (DPM, 2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido(5,4-d)py rim idine) against xanthine oxidase (XO), carbonic anhydorase (CA) and monoamine oxidase (MAO) were studied, in vitro. DPM did not inhibit XO and CA, but it strongly inhibited MAO. The type of inhibition by DPM against MAO with respect to benzylamine as a substrate was uncompetitive. |
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