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Biosynthesis, production and applications of bacterial cellulose
Authors:Shin-Ping Lin  Iris Loira Calvar  Jeffrey M Catchmark  Je-Ruei Liu  Ali Demirci  Kuan-Chen Cheng
Institution:1. Institute of Biotechnology, National Taiwan University, 1, Sec 4, Roosevelt Rd., Taipei, 10617, Taiwan
2. Food Technology Department, Higher Technical School of Agricultural Engineering, Technical University of Madrid, 28040, Madrid, Spain
3. Department of Agricultural and Biological Engineering, The Pennsylvania State University, University Park, PA, 16802, USA
4. Center for NanoCellulosics, The Pennsylvania State University, University Park, PA, 16802, USA
5. Graduate Institute of Food Science Technology, National Taiwan University, Taipei, 10617, Taiwan
Abstract:Bacterial cellulose (BC) as a never-dried biopolymer synthesized in abundance by Gluconacetobacter xylinus is in a pure form which requires no intensive processing to remove unwanted impurities and contaminants such as lignin, pectin and hemicellulose. In contrast to plant cellulose, BC, with several remarkable physical properties, can be grown to any desired shape and structure to meet the needs of different applications. BC has been commercialized as diet foods, filtration membranes, paper additives, and wound dressings. This review article presents an overview of BC structure, biosynthesis, applications, state-of-the-art advances in enhancing BC production, and its material properties through the investigations of genetic regulations, fermentation parameters, and bioreactor design. In addition, future prospects on its applications through chemical modification as a new biologically active derivative will be discussed.
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