Morphology and size controlled synthesis of Co-doped MIL-96 by different alkaline modulators for sensitively detecting alpha-fetoprotein |
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Institution: | 1. Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, China;2. School of Chemistry and Chemical Engineering, Guangling College, Yangzhou University, Yangzhou 225009, China;3. School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou 450001, China;1. Guangling College, Yangzhou University, Yangzhou 225009, China;2. School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225009, China;1. School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, Jiangsu, PR China;2. Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, 450002 Zhengzhou, PR China |
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Abstract: | This work introduces a simple and facile approach for the morphology and size controlled synthesis of Co-doped MIL-96. By using different bases as modulators, Co-doped MIL-96 was obtained with sizes that varied from 5 μm to 300 nm, and four different morphologies, including hexagonal prism, icosahedron, hexagonal spindle and ellipsoid. Among these, nano-sized Co-doped MIL-96 with an ellipsoid morphology exhibited the highest electroactive surface area and good conductivity as well as the best electrochemical sensing performance towards α-fetoprotein. |
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Keywords: | Morphology/size MIL-96 Modulator Aptasensor Alpha-fetoprotein |
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