Preparation of 8‐Aza‐7‐deazaaristeromycin and ‐neplanocin A and Their 5′‐Homologs |
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Authors: | Haisheng Wang Yan Zhang Wei Ye Stewart W Schneller |
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Institution: | Molette Laboratory for Drug Discovery, Department of Chemistry and Biochemistry, Auburn University, Auburn, AL, USA |
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Abstract: | The synthesis of new members of the aristeromycin and neplaoncin A families of carbocyclic nucleosides possessing the 1H‐pyrazolo3,4‐d]pyrimidine ring is reported. For this purpose, an adapted route to 4‐amino‐1H‐pyrazolo3,4‐d]pyrimidine is described. |
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Keywords: | 8‐aza‐7‐deazaadenine carbocylic nucleosides |
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