Novel One‐Pot Three‐Component Reaction for the Synthesis of Functionalized Spiroquinazolinones |
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| Authors: | Mahdieh Tajbakhsh Sorour Ramezanpour Saeed Balalaie Hamid Reza Bijanzadeh |
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| Institution: | Peptide Chemistry Research Center, K. N. Toosi University of Technology, Tehran, Iran |
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| Abstract: | A wide variety of spiroquinazolinone derivatives have been synthesized via a one‐pot three‐component reaction of isatoic anhydride, cyclic ketones, and hydrazides in the presence of catalytic amount (20 mol%) of H3PO3 in ethanol. Mild reaction conditions, high atom economy, operational simplicity, and good to high yields are the key advantages of the present protocol. |
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| Keywords: | Spiroquinazolinone One‐pot three‐component reaction Hydrazides |
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