Clean and Efficient Synthesis of Pyrazole Derivatives in Aqueous Media |
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| Authors: | Pan Xu Yu‐Kun Xi Hui Chen Da‐Qing Shi |
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| Affiliation: | Key Laboratory of Organic Synthesis of Jiangsu Province, Soochow University, Suzhou, People's Republic of China |
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| Abstract: | A series of 5‐aryl‐1H‐pyrazole derivatives were synthesized via the reaction of 3‐(dimethylamino)‐1‐arylprop‐2‐en‐1‐one with hydrazine in aqueous media without using any catalyst. This method has the advantages of easier work‐up, mild reaction condition, high yields, and an environmentally benign procedure. |
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