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CuBr-catalyzed efficient alkynylation of sp3 C-H bonds adjacent to a nitrogen atom
Authors:Li Zhiping  Li Chao-Jun
Affiliation:Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 2K6, Canada.
Abstract:A simple and effective catalytic method to construct propargylamine was developed by using copper bromide and tert-BuOOH via a combination of sp3 C-H bond and sp C-H bond activations followed by C-C bond formation.
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