CuBr-catalyzed efficient alkynylation of sp3 C-H bonds adjacent to a nitrogen atom |
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Authors: | Li Zhiping Li Chao-Jun |
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Affiliation: | Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 2K6, Canada. |
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Abstract: | A simple and effective catalytic method to construct propargylamine was developed by using copper bromide and tert-BuOOH via a combination of sp3 C-H bond and sp C-H bond activations followed by C-C bond formation. |
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