Operator-valued free Fisher information and modular frames

We introduce the operator-valued free Fisher information for a random variable in an operator-valued noncommutative probability space and point out its relations to the amalgamated freeness. Using M. Frank and D. Larson's modular frame notion we can construct the conjugate variable for an operator-valued semicircle variable with conditional expectation covariance. Then we obtain its free Fisher information and show it is equal to the index of the conditional expectation. At last the conjugate variable with respect to a modular frame operator for a semicircle variable is also constructed.