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Recent progress toward the total synthesis of humulanolides |
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| Authors: | Jing-Chun Han Xin Liu Jing Zhao Shaoping Li Chuang-Chuang Li |
| Affiliation: | 1. Department of Chemistry, South University of Science and Technology of China, Shenzhen, 518055, China;2. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China;3. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China |
| Abstract: | The humulanolides are a series of sesquiterpene lactones, most of which have unique and challenging structure. The humulanolides have exhibited anticancer activity. The combinations of fascinating structural motifs and promising pharmacological properties have prompted significant interest in the synthetic community. In this review, we provide a summary of recent progress regarding the total synthesis of humulanolides. |
| Keywords: | Natural products Humulanolide Asteriscanolide Total synthesis |
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