Cyclization-Carbonylation-Cyclization Coupling Reaction of Propargyl Ureas with Palladium(II)-Bisoxazoline Catalyst |
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Authors: | Taichi Kusakabe Koujiro Kawaguchi Miya Kawamura Naohiko Niimura Rong Shen Hiroyuki Takayama Keisuke Kato |
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Affiliation: | Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. h.takayama@nichiyaku.ac.jp. |
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Abstract: | The cyclization-carbonylation-cyclization coupling reaction (CCC-coupling reaction) of propargyl ureas catalyzed by PdII(box) complexes afforded symmetrical ketones bearing two 2-amino-2-oxazoline groups in good to moderate yields. |
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