Synthesis of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acids,intermediate products in the synthesis of cis-4-Aminochroman-3-ols |
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| Authors: | Z. A. Bredikhina A. V. Pashagin A. V. Kurenkov A. A. Bredikhin |
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| Affiliation: | 1. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia
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| Abstract: | ![]()
Oxidation of accessible (R)-3-chloropropane-1,2-diol to (R)-3-chloro-2-hydroxypropanoic acid and subsequent reaction of the latter with ortho-substituted sodium phenoxide gave a number of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acid which are intermediate products in the synthesis of nonracemic 4-aminochroman-3-ols. |
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