Photochemical studies on acyclic alkyl aromatic ketones in the solid state: asymmetric induction and increased chemoselectivity |
| |
| Authors: | Manling Ma Wei Feng Fang Guo Chao Yang Wujiong Xia |
| |
| Institution: | 1. The State Key Lab of Urban Water Resource and Environment & the Academy of Fundamental and Interdisciplinary Science, Harbin Institute of Technology, PO Box 3026, 2# Yikuang Street, Harbin, Heilongjiang, PR China;2. State Key Lab of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China |
| |
| Abstract: | The acyclic alkyl aromatic ketones, 2-isobutyl-4-methyl-1-arylpentan-1-one derivatives were designed and synthesized for photochemical investigations. Irradiation of such compounds in acetonitrile solution led to the Yang cyclization and Norrish type II cleavage photoproducts with a ratio of 1:1, whereas the reaction conducted in the solid state using the ionic chiral auxiliary method led to only the Yang cyclization product with as high as 99% ee. Furthermore, the conformational transitions were first observed in the reaction. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
