Synthesis of highly N-substituted indole library via conjugate additions of indoline and their synthetic tool potentials |
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| Authors: | Haydar Kilic Sinan Bayindir Esra Erdogan Nurullah Saracoglu |
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| Institution: | 1. Department of Chemistry, Faculty of Sciences, Atatürk University, Erzurum 25240, Turkey;2. Department of Chemistry, Faculty of Sciences and Arts, Bingöl University, Bingöl 12000, Turkey |
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| Abstract: | A comprehensive library of N- or 1-substituted indoles was formed by conjugate additions of indoline with Michael acceptors followed by an oxidation step. Using N-substituted indoles as key Michael donors, the synthesis of 1,3-disubstituted indoles was also accomplished. |
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