| An Unusual Formation of Cyclic Sulfite at C-4 and C-5 Positions of Taxane |
| |
| 作者姓名： | MengZHANG DaLiYIN JiYuGUO XiaoTianLIANG |
| |
| 作者单位： | InstituteofMateriaMedica,ChineseAcademyofMedicalScience＆PekingUnionMedicalCollege,Beijing100050 |
| |
| 摘 要： | An unusual formation of cyclic sulfite at C-4 and C-5 positions of taxane was accomplished by treatment of compound 1 with excess MeSOEC1/Et3N and a possible mechanism was proposed.
|
| 关 键 词： | 环亚硫酸盐 C-4位置 C-5位置 作用机理 甲磺酰化 紫杉醇 抗癌物质 合成 |
An Unusual Formation of Cyclic Sulfite at C-4 and C-5 Positions of Taxane |
| |
| MengZHANG DaLiYIN JiYuGUO XiaoTianLIANG.An Unusual Formation of Cyclic Sulfite at C-4 and C-5 Positions of Taxane[J].Chinese Chemical Letters,2004,15(9):1033-1035. |
| |
| Authors: | Meng ZHANG Da Li YIN Ji Yu GUO Xiao Tian LIANG Institute of Materia Medica Chinese Academy of Medical Science & Peking Union Medical College Beijing |
| |
| Institution: | Meng ZHANG,Da Li YIN*,Ji Yu GUO,Xiao Tian LIANG Institute of Materia Medica,Chinese Academy of Medical Science & Peking Union Medical College,Beijing 100050 |
| |
| Abstract: | An unusual formation of cyclic sulfite at C-4 and C-5 positions of taxane was accomplished by treatment of compound 1 with excess MeSO2Cl/Et3N and a possible mechanism was proposed. |
| |
| Keywords: | Paclitaxel taxane mesylation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
