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Studies with enamines and azaenamines: A novel efficient route to 6‐amino‐1,4‐dihydropyridazines and their condensed derivatives
Authors:Said A S Ghozlan  Ismail A Abdelhamid  Hamdi M Hassaneen  Mohamed H Elnagdi
Institution:Department of Chemistry, Faculty of Science, Cairo University, Giza, A. R. Egypt
Abstract: chemical structure image 1‐Arylhydrazonopyruvaldehydes 1 react with α,β‐unsaturated nitriles 2 to yield 6‐amino‐1,4‐dihydropyridazines 4 that are converted into pyridazinones 5 via refluxing in an acetic acid/hydrochloric acid mixture and into the ethylidenemalononitrile derivatives 6 on reflux with malononitrile in ethanolic/piperidine solution.
Keywords:
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