Langmuir — Blodgett deposition of lipid films on hydrogel as a basis for biosensor development |
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Authors: | A. Arya U.J. Krull Michael Thompson H.E. Wong |
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Affiliation: | Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 1A1 Canada |
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Abstract: | Lipid membranes composed of phosphatidyl choline and cholesterol were interfaced to polyacrylamine hydrogen by Langmuir—Blodgett thin-film deposition. The extent of lipid adsorption to the gel surface was critically dependent on the hydration of the polymer as determined by contact angle measurements. Some electrochemical transducers incorporating the deposited membrane/gel structure responded positively to phloretin and valinomycin. Limitations to the construction of this device are discussed. |
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