|
|||||
|
|
| (E)-烯基甲苯基硅醇的合成 | |
| 引用本文： | 冯维春,王东,李连海. (E)-烯基甲苯基硅醇的合成[J]. 有机化学, 1992, 12(4): 372-377 |
| 作者姓名： | 冯维春 王东 李连海 |
| 作者单位： | 中国科学院化学研究所，中国科学院化学研究所，中国科学院化学研究所 北京，100080，北京，100080，北京，100080 |
| 摘 要： | 从烯丙基甲苯基氨基硅烷出发,经过基化反应,得到(E)-烯基氨基硅烷, 然后水解成(E)-烯基硅醇。研究了烯丙基氨硅烷碳负离子烷基化学反应的区域选择性,建立了去除α-异构体的方法。 |
| 关 键 词： | 选择性 烷基化 硅烷 烯丙基 硅烷醇 |
Synthesis of (E)-alkenylmethylphenylsilanols |
|
| FENG Wei-Chun,WANG Dong,LI Lian-Hai Institute of Chemistry,Academia Sinica,Beijing. Synthesis of (E)-alkenylmethylphenylsilanols[J]. Chinese Journal of Organic Chemistry, 1992, 12(4): 372-377 | |
| Authors: | FENG Wei-Chun WANG Dong LI Lian-Hai Institute of Chemistry Academia Sinica Beijing |
| Affiliation: | FENG Wei-Chun,WANG Dong,LI Lian-Hai Institute of Chemistry,Academia Sinica,Beijing 100080 |
| Abstract: | Starting from allylmethylphenylaminosilanes, (E)-alkenyl(methyl)phenylsilanols were synthesized through alkylation of allyl(amino)silane carbanions with halides, followed by hydrolysis of alkenyl(amino)silane, which was produced in the alkylation, under very mild condition. Regioselectivity of the alkylation was studied, and the method for removing a-isomer out from the mixture of the product was developed. E.g., aminosilane I was lithiated, alkylated with n-pentyl iodide to give, after refluxing with NaI and Me3SiCl in EtOH, 83% II (R = n-pentyl, R1 = Et)(III). Hydrolysis of III gave 72% silanol II (R = n-pentyl, R1 = H). |
| Keywords: | allylaminosilane carbanion alkylation regioselectivity alkenylsilanol |
| 本文献已被 CNKI 维普 等数据库收录！ | |
| 点击此处可从《有机化学》浏览原始摘要信息 | |
| 点击此处可从《有机化学》下载全文 | |