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Methyltriazolocoumarins: New furocoumarin isosters as potential photochemotherapeutic agents
Authors:P. Rodighiero  A. Chilin  G. Pastorini  A. Guiotto  P. Manzini
Abstract:A number of new methyltriazolocoumarins with a linear psoralen-like structure or an angular angelicin-like structure were synthetized. The syntheses were performed starting from the appropriate methylated 7-aminocoumarins which were nitrated, reduced and successively diazotized with concomitant cyclization to form the condensed triazolo ring. The new methyltriazolocoumarins show promising spectroscopic properties which are potentially predictive of their photochemical and photobiological behaviour.
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