An efficient HCCP-mediated direct amination of quinazolin-4(3H)-ones |
| |
| Authors: | Zhenlu ShenXiaofei He Jialiang DaiWeimin Mo Baoxiang HuNan Sun Xinquan Hu |
| |
| Institution: | a College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, PR China
b State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China |
| |
| Abstract: | An efficient direct amination of quinazolin-4(3H)-ones has been developed. Treatment of quinazolin-4(3H)-ones with HCCP, DIPEA, and N-contained nucleophiles in acetonitrile could be able to form the corresponding 4-aminoquinazoline derivatives. Under the optimal reaction conditions, the amination products were achieved in good yields. |
| |
| Keywords: | Amination Quinazolin-4(3H)-ones 4-Aminoquinazolines Hexachlorocyclotriphosphazene |
| 本文献已被 ScienceDirect 等数据库收录！ |
