新型N,N′-二(邻氧乙酸)苄叉乙二胺合钴(Ⅱ)和N-(邻氧乙酸)苄叉乙二胺合铜(Ⅱ)的合成、 晶体结构及生物有效性研究

在水溶液中, 将N,N′-二(邻氧乙酸)苄叉乙二胺(1)与氯化钴(Ⅱ)反应, 获得配合物Co(Ⅱ)L1·H2O(2)［L1=N,N′-二(邻氧乙酸)苄叉乙二胺］; 将邻氧乙酸苯甲醛、 乙二胺与氯化铜(Ⅱ)反应, 获得Cu(Ⅱ)ClL2·2H2O(3)［L2=N-(邻氧乙酸)苄叉乙二胺］. 用元素分析、 1 H NMR和IR等方法对所合成的化合物1和配合物2和3进行了结构表征, 并测定了配合物2和3的晶体结构. 黄豆种子经不同浓度配合物2和3处理均能萌发, 但发芽率、 发芽指数和活力指数均比对照组低， 说明配合物2和3随着溶液浓度的增加对黄豆种子萌发和幼苗生长产生一定的阻滞作用.

Synthesis, Crystal Structure and Bioactivity of two Novel Complexes N,N′-Bis(o-oxy-acetate)benzylethylenediamine with Co(Ⅱ) and N-(o-oxy-acetate)benzylethylene Diamine with Cu(Ⅱ)

The complex Co(Ⅱ)L1·H2O(2)［L1=N,N′-bis(o-oxy-acetate)benzylethylene diamine(1)］ was synthesized by the reactions of compound 1 and Co(Ⅱ) dichloride in the solvents of water, and Cu(Ⅱ)ClL2·2H2O(3)［L2=N-(o-oxy acetate)benzylethylene diamine］ was prepared by o-oxy-acetatebenzaldehyde, ethylene diamine and Cu(Ⅱ) dichloride through one step procedure in water. Complexes 2 and 3 were characterized by elemental analysis, 1H NMR, FTIR spectroscopy and single crystal X-ray diffraction analysis. There are two independent molecules(host molecule) and two water molecules(guest molecule) in one asymmetric unit of complex 2, the Co(Ⅱ) atom exhibits a distorted trigonal prismatic column geometry. There are one molecule(host molecule) and two water molecules in each unit of complex 3, the Cu(Ⅱ) atom exhibits a distorted square cone geometry. Simultaneously, the effects of different concentration levels of complexes 2 and 3 on germination and seedling growth of soybean seeds were investigated through experiment. It can be concluded that soybean seeds could germinate at all of the four concentrations of complexes 2 and 3. But germination percentage, rate of germination and index of vigor were lower than control, which illustrated that as concentration of complexes 2 and 3 increased, germination and seedling growth of soybean seeds were blocked.