Synthesis of (s)-(-)-Benzyl-2-tert-butoxycarbonyl amino-4-iodobutyrate |
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| Authors: | Xin Rong QIN Quan LI Yu Yuan XIE State Key Laboratory of Drug Research |
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| Institution: | Xin Rong QIN*,Quan LI,Yu Yuan XIE State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Shanghai Institutes for Biological Sciences,Chinese Academy of Science,Shanghai 200031 |
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| Abstract: | A convenient method to synthesize (s)-(-)-benzyl-2-tert-butoxy carbonylamino-4-iodobutyrate from L-(+)methionine 1 was reported, the enantiomeric purity of the product was established by comparison of optical rotation data with literature values, indicating that the reaction process occurred without racemization. |
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| Keywords: | Amino acid chiral |
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