Molecular Recognition of Nucleic Acid Bases in Water by Hydrogen Bonding of Poly(vinyldiaminotriazine) |
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| Authors: | Hiroyuki Asanuma Sumie Gotoh Takeshi Ban Makoto Komiyama |
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| Affiliation: | (1) Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113, Japan |
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| Abstract: | Poly(2-vinyl-4,6-diamino-1,3,5-triazine) efficiently binds nucleic acid bases and nucleosides in water by using complementary hydrogen bonding. The binding activity decreases in the order: U, T > A  C, G. The corresponding monomer shows virtually no activity, indicating a predominant role of polymer effect for the molecular recognition in water. |
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| Keywords: | Poly(2-vinyl-4,6-diamino-1,3,5-triazine) molecular recognition hydrogen bonding nucleic acid base |
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