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| 傅里叶变换中红外光谱法检测脑膜瘤的研究 | |
| 引用本文： | Wan WQ,Pan QH,Jia GJ,Xu YZ,Lai GQ,Liu SX,Chen J,Yang LM,Zhang YF,Weng SF,Wu JG. 傅里叶变换中红外光谱法检测脑膜瘤的研究[J]. 光谱学与光谱分析, 2011, 31(2): 353-356. DOI: 10.3964/j.issn.1000-0593(2011)02-0353-04 |
| 作者姓名： | Wan WQ Pan QH Jia GJ Xu YZ Lai GQ Liu SX Chen J Yang LM Zhang YF Weng SF Wu JG |
| 作者单位： | 1. 首都医科大学附属北京天坛医院,北京,100083 2. 北京大学化学与分子工程学院,北京,100871;杭州师范大学有机硅化学与材料重点实验室,浙江,杭州,310012 3. 北京大学化学与分子工程学院,北京,100871 4. 杭州师范大学有机硅化学与材料重点实验室,浙江,杭州,310012 |
| 基金项目： | 国家自然科学基金项目(30371604,50203001和20171004,50973003)资助 |
| 摘 要： | 采用傅里叶变换衰减全反射中红外光谱法检测了24例液氮冻存的脑膜瘤离体样品(其中良性肿瘤12例,有恶性倾向的肿瘤12例),对得到的红外光谱进行整理分析,发现不同类型脑膜瘤组织(如纤维型脑膜瘤和内皮型脑膜瘤)的红外光谱存在着差异,并且同一种类型的脑膜瘤组织,其恶性倾向的程度不同,他们的红外光谱也表现出较为明显的区别,因此,我们可以从各个特征吸收峰的峰位、峰形及峰强等信息的变化来区分脑膜瘤,并可以初步鉴别脑膜瘤的性质;研究结果发现,通过某些特征吸收峰(如1 160cm-1)峰位的变化来鉴别脑膜瘤的性质与病理诊断结果的符合率大于85%,说明傅里叶变换衰减全反射中红外光谱法有可能发展成为一种对样品无损伤、快速的脑肿瘤诊断新方法。 |
| 关 键 词： | 傅里叶变换中红外光谱 衰减全反射 脑膜瘤 |
Study on the meningoima using FT-mid-IR spectroscopy |
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| Wan Wei-Qing,Pan Qing-Hua,Jia Gui-Jun,Xu Yi-Zhuang,Lai Guo-Qiao,Liu Shao-Xuan,Chen Jing,Yang Li-Min,Zhang Yuan-Fu,Weng Shi-Fu,Wu Jin-Guang. Study on the meningoima using FT-mid-IR spectroscopy[J]. Spectroscopy and Spectral Analysis, 2011, 31(2): 353-356. DOI: 10.3964/j.issn.1000-0593(2011)02-0353-04 | |
| Authors: | Wan Wei-Qing Pan Qing-Hua Jia Gui-Jun Xu Yi-Zhuang Lai Guo-Qiao Liu Shao-Xuan Chen Jing Yang Li-Min Zhang Yuan-Fu Weng Shi-Fu Wu Jin-Guang |
| Affiliation: | WAN Wei-qing2,PAN Qing-hua1,3,JIA Gui-jun2,XU Yi-zhuang1,LAI Guo-qiao3,LIU Shao-xuan1,CHEN Jing1,YANG Li-min1,ZHANG Yuan-fu1,WENG Shi-fu1,WU Jin-guang1 1.College of Chemistry and Molecular Engineering,Peking University,Beijing 100871,China 2.Beijing Tian Tan Hospital Affiliated to Capital Medical University,Beijing 100083,China 3.Laboratory of Organosilicon Chemistry and Material Technology,Hangzhou Normal University,Hangzhou 310012,China |
| Abstract: | In the present investigation,24 cases of meningoima tissues(including 12 cases of benign tumor and 12 cases of malignant tumor 12) were detected using FT-mid-IR spectroscopy linked with attenuated total reflectance(ATR) accessory.These FTIR spectra obtained from the above-mentioned meningoima tissues were analyzed and compared.Significant differences were found in the spectral features of different kinds of meningoima tissues for example fibrous type meningoima and endothelioid meningoima;and for the same t... |
| Keywords: | FT-mid-IR Attenuate total reflection(ATR) Meningoima |
| 本文献已被 CNKI 万方数据 PubMed 等数据库收录！ | |