An alternative stereoselective synthesis of greensporone C |
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| Authors: | Venkata Naresh Vema Y. Bharathi kumari Sridhar Musulla RamaKrishnam Raju Addada Srinivasa Rao Alapati |
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| Affiliation: | 1. GVK Biosciences Private Limited, Medicinal Chemistry Divison 28A, IDA, Nacharam, Hyderabad 500076, Telangana, India;2. Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad 500 085, Telangana, India |
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| Abstract: | ![]()
Greensporone C, a new 14-membered resorcylic acid lactone, has been synthesized from inexpensive and commercially available starting materials. This convergent synthesis utilizes Cross metathesis using the Grubbs Hoveyda catalyst, alkylation of 1,3-dithiane and Yamaguchi macrolactonization as key steps. |
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| Keywords: | Greensporone C Resorcylic acid lactones Cross metathesis Grubbs Hoveyda catalyst Yamaguchi macrolactonization |
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