Synthesis of a new fluorescent probe specific for catechols |
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Authors: | Stack Douglas E Hill Anastacia L Diffendaffer Clark B Burns Nicole M |
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Affiliation: | Department of Chemistry, University of Nebraska at Omaha, 6001 Dodge Street, 68182-0109, USA. destack@unomaha.edu |
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Abstract: | [reaction: see text] The synthesis of a new fluorescent probe, specific for the catechol moiety, has been conducted by preparation of alpha,alpha-dibromomalonamides containing an appropriate fluorophore. N,N'-Bis-anthracen-9-ylmethyl-2,2-dibromomalonamide reacted with various catechols in the presence of cesium carbonate to generate highly fluorescent derivatives. |
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