Modeling the migration of cancer cells in the bloodstream |
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| Authors: | Y. L. R. Quek T. L. Lai K.-H. Chiam |
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| Affiliation: | A*STAR Institute of High Performance Computing, 1 Science Park Road #01-01, Singapore 117528, Singapore |
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| Abstract: | ![]()
We model the migration of cancer cells that have broken away from a tumor and are circulating in the bloodstream. Using the immersed boundary method and culling from literature the material properties of cancer cells, we simulate how cells deform as a function of the flow properties of the bloodstream as well as the adhesive properties between the cancer cells and the endothelial cells of the bloodstream. We also simulate the migration characteristics as a function of the migrating cell density. (© 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) |
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