The use of umbelliferone in the synthesis of new heterocyclic compounds |
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| Authors: | Al-Amiery Ahmed A Musa Ahmed Y Kadhum Abdul Amir H Mohamad Abu Bakar |
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| Institution: | Department of Chemical and Processing Engineering, Faculty of Engineering and Built Environment, University of Kebangsaan Malaysia, Bangi, Selangor 43600, Malaysia. dr.ahmed@eng.ukm.my |
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| Abstract: | New coumarin derivatives, namely 7-(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one, 5-(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one, 2-2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide, 7-(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one and 7-(5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)methoxy]-2H-chromen-2-one were prepared starting from the natural compound umbelliferone. The newly synthesized compounds were characterized by elemental analysis and spectral studies (IR, 1H-NMR and 13C-NMR). |
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