| 左截断双删失数据下可加可乘风险率模型的估计 |
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| 引用本文： | 杨琳,房厦,郭航.左截断双删失数据下可加可乘风险率模型的估计[J].数理统计与管理,2017(2):263-272. |
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| 作者姓名： | 杨琳 房厦 郭航 |
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| 作者单位： | 首都经济贸易大学统计学院,北京,100070 |
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| 基金项目： | 国家自然科学基金项目(11671267)，首都经济贸易大学研究生科技创新项目;首都经济贸易大学2016年促进高校内涵发展定额青年教师科研启动基金(00591654490336)，首都经济贸易大学科研水平提高定额项目资助 |
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| 摘 要： | 在生存分析中,可加可乘风险率模型常用来研究协变量对初始事件和终止事件之间持续时间的影响效应。在本文中,我们考虑了在初始事件存在部分区间删失,同时终止事件存在左截断右删失的情形下,持续时间的可加可乘风险率模型的估计问题。我们提出了一个两阶段估计过程来估计模型的回归参数。并通过模拟分析验证了估计的大样本性质。最后利用该方法分析了恶性黑色素瘤手术治疗数据。
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| 关 键 词： | 可加可乘风险率模型 左截断双删失 非参数条件极大似然 |
Estimation of Additive-multiplicative Hazards Model with Left Truncated and Doubly Censored Data |
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| YANG Lin,FANG Sha,GUO Hang.Estimation of Additive-multiplicative Hazards Model with Left Truncated and Doubly Censored Data[J].Application of Statistics and Management,2017(2):263-272. |
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| Authors: | YANG Lin FANG Sha GUO Hang |
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| Abstract: | In survival studies,additive-multiplicative hazards model is often used to analyze covariate effects on the duration time,defined as elapsed time between the initial event and the terminal event.In this article,we consider the situation when the initial event suffers partly interval censoring and the terminal event suffers left truncation and right censoring.We proposed a two-step estimation procedure for estimating the regression coefficients of the additive-multiplicative hazards model on the duration time.Simulation studies are conducted to investigate the performance of the proposed estimator.The proposed method is applied to the malignant melanoma surgery treatment data. |
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| Keywords: | additive-multiplicative hazards model left truncated and doubly censored nonparametric conditional maximum likelihood |
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