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Caspases: key mediators of apoptosis |
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| Institution: | Merck Research Laboratories, R80w-250, PO Box 2000, Rahway, NJ 07065, USA |
| Abstract: | Recent studies have established that members of the caspase protease family are essential components of a conserved cell death program. Insights into their biological roles, structure and mechanism are enabling investigators to begin to explore the therapeutic potential of caspase inhibition. |
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