| Synthesis, Dimeric Crystal Structure, and Biological Activities of N- （ 4-Methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl ） -N＇- （ 2-trifluoromethyl-phenyl ） -guanidine |
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| 作者姓名： | HE Feng-qi WANG Bao-lei LI Zheng-ming |
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| 作者单位： | Elemento-Organic Chemistry Institute, State-Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China |
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| 基金项目： | Supported hy the National Basic Research Program of China（ No. 2003CB114406）. |
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| 摘 要： | The title compound, N-（4-methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl）-N＇-（2-tritluoromethyl-phenyl）-guanidine, was synthesized and its structure was confirmed by using IR, MS,^1H NMR, and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test showed that the synthesized compound has a weak herbicidal activity.
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| 关 键 词： | 合成 二聚晶体结构 酮醇-酸还原异构酶 X-射线衍射 生物活性 嘧啶 |
| 文章编号： | 1005-9040（2006）-06-768-04 |
| 收稿时间： | 2005-10-17 |
Synthesis, Dimeric Crystal Structure, and Biological Activities of N-(4-Methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl)-N′-(2-trifluoromethyl-phenyl)-guanidine |
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| HE Feng-qi WANG Bao-lei LI Zheng-ming.Synthesis, Dimeric Crystal Structure, and Biological Activities of N-(4-Methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl)-N′-(2-trifluoromethyl-phenyl)-guanidine[J].Chemical Research in Chinese University,2006,22(6):768-771. |
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| Authors: | Feng-qi HE Bao-lei WANG Zheng-ming LI |
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| Institution: | aElemento-Organic Chemistry Institute, State-Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China |
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| Abstract: | The title compound, N-(4-methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl)-N′-(2-trifluoromethyl-phenyl)-guanidine, was synthesized and its structure was confirmed by using IR, MS, 1H NMR, and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test showed that the synthesized compound has a weak herbicidal activity. |
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| Keywords: | Ketol-acid reductoisomerase Synthesis X-ray diffraction Crystal structure Biological activity |
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