| 安尔眠糖浆剂型改良与质量控制 |
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| 引用本文： | 凌立新,张国芬.安尔眠糖浆剂型改良与质量控制[J].化学研究与应用,2012,24(5):825-828. |
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| 作者姓名： | 凌立新 张国芬 |
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| 作者单位： | 1. 重庆文理学院化学与环境工程学院,重庆永川,402160
2. 成都华高药业有限公司,四川成都,610041 |
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| 摘 要： | 本文建立了安尔眠糖浆剂型改良成丸剂的制备工艺及其含量测定的方法。结果表明,制备工艺稳定、可行。用HPLC法测定安尔眠丸的含量,在0.25～1.23μg范围内,线性关系良好,平均加样回收率为99.68%,RSD为1.33%。该测定方法简便,结果可靠,重现性好,可作为安尔眠丸的含量测定方法。
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| 关 键 词： | 安尔眠丸 改剂型 质量控制 高效液相色谱法 |
Preparation and quality control of An'ermian pill |
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| LING Li-xin
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ZHANG Guo-fen.Preparation and quality control of An'ermian pill[J].Chemical Research and Application,2012,24(5):825-828. |
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| Authors: | LING Li-xin ZHANG Guo-fen |
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| Institution: | 1.College of Chemistry and Environmental Engineering,Chongqing University of Arts and Sciences,Yongchuan 402160,China; 2.Chengdu Wagott Pharmaceutical Co.,Ltd,Chengdu 610041,China) |
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| Abstract: | To establish a method for the change of dose-form of An′ermian syrup and introduce a method for quality control of An’ermian pill.The results showed that the technology process was stable and feasible.The HPLC method for the determination of the content,the linear ranges were 0.25μg～1.23μg,and its sample recovery was 99.68%,RSD=1.33%.The trial shows that this method is simple,reliable and of good repeatability.It can be used for the quality control of the An’ermian pill. |
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| Keywords: | An′ermian pill change dose-form quality control HPLC |
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