| pH敏感阳离子聚电解质凝胶的溶胀和释药性能 |
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| 引用本文： | 严俊,周春才.pH敏感阳离子聚电解质凝胶的溶胀和释药性能[J].应用化学,2000,17(1):75-0. |
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| 作者姓名： | 严俊 周春才 |
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| 作者单位： | 华东师范大学 |
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| 摘 要： | 共聚物;pH敏感阳离子聚电解质凝胶的溶胀和释药性能
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| 关 键 词： | 共聚物 pH敏感阳离子聚电解质凝胶的溶胀和释药性能 |
| 收稿时间： | 2009-06-29 |
| 修稿时间： | 2009-06-29 |
Swelling and Drug Release Behavior of pH-Sensitive Cationic Polyelectrolyte Gels |
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| YAN Jun,ZHOU Chun-Cai.Swelling and Drug Release Behavior of pH-Sensitive Cationic Polyelectrolyte Gels[J].Chinese Journal of Applied Chemistry,2000,17(1):75-0. |
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| Authors: | YAN Jun ZHOU Chun-Cai |
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| Abstract: | A series of pH sensitive cationic polyelectrolyte gel beads were prepared by suspension copolymerization of styrene or methyl methacrylate with diethylaminoethyl methacrylate and divinylbenzene . The study on the swelling behavior of the gels showed that the hydrophobic/hydrophilic composition of the gels had a great influence on the phase transition pH value and the swelling ability of the gels. Both the equilibrium swelling capacity and the swelling rate were pH dependent. The drug release behavior of the gels were well correlated with the swelling behavior of the gels. |
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| Keywords: | copolymer cationic polyelectrolyte gel swelling drug release |
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