| Sterols from the Fungus Catathelasma imperiale |
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| 作者姓名： | 杨升平 徐军 岳建民 |
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| 作者单位： | StateKeyLaboratoryofDrugResearch,InstituteofMateriaMedica,ShanghaiInstituteforBiologicalSciences,ChineseAcademyofSciences,Shanghai201203,China |
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| 基金项目： | ProjectsupportedbytheNationalNaturalScienceFoundationofChina (No .30025044)andtheFoundationfromtheMinistryofScienceandTechnologyofChina (No .2 0 0 2CB5 12 80 7) |
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| 摘 要： | Eight ergostane-type sterols and three their derivatives (one mono-linoleate and two mono-glucosides) were isolated from the ethyl acetate soluble fraction of the fungus Catathelasma imperi.a/e. Two of them are novel compounds, namely 22E,24R-er-gosta-7,22-diene-3β ,5α-diol-6β-linoleate (1) and 22E, 24R-er-gosta-7,22-diene-3β, 5β, 6α-triol (5) with an uncommon c/s-fused A/B ring. Structures of these compounds were demon-strated on the basis of their chemical evidences and spectroscop-ic methods, especially 2D NMR techniques.
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| 关 键 词： | 甾醇类 真菌 分离 生物活性 核磁共振分析 天然化合物 |
Sterols from the Fungus Catathelasma imperiale |
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| YANG,Sheng Ping XU,Jun YUE,Jian Min State Key Laboratory of Drug Research.Sterols from the Fungus Catathelasma imperiale[J].Chinese Journal of Chemistry,2003,21(10):1390-1394. |
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| Authors: | YANG Sheng Ping XU Jun YUE Jian Min State Key Laboratory of Drug Research |
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| Institution: | YANG,Sheng Ping XU,Jun YUE,Jian Min State Key Laboratory of Drug Research,Institute of Materia Medica,Shanghai Institute for Biological Sciences,Chinese Academy of Sciences,Shanghai 201203,China |
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| Abstract: | Eight ergostane‐type sterols and three their derivatives (one mono‐linoleate and two mono‐glucosides) were isolated from the ethyl acetate soluble fraction of the fungus Catathelasma imperiale. Two of them are novel compounds, namely 22E, 24R‐ergosta‐7,22‐diene‐3β,5α‐diol‐6β‐inoleate (1) and 22E,24R‐ergosta‐7,22‐diene‐3β,5β,6α‐triol (5) with an uncommon cis‐fused A/B ring. Structures of these compounds were demonstrated on the basis of their chemical evidences and spectroscopic methods, especially 2D NMR techniques. |
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| Keywords: | fungus Catathelasma imperiale sterol |
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